ChemoSHIELD^® Barrier Isolator (negative pressure)

ChemoSHIELD® Barrier Isolator (negative pressure) The ChemoSHIELD® Barrier Isolator (negative pressure) Model CS500 shown with front viewscreen closed and locked. Constructed to UL standards for performance and safety Personnel, Product and Environment. Offers environmental protection from vapors and gases only if exhausted to treated exhaust system Click here to download product literature Fixed Position, Standing Model CS500 shown Fixed Position, Seated Model CS500 shown ChemoSHIELD® Barrier Isolator (negative pressure), with adjustable mounting stand can be configured for standing or sitting operation. Hard exhaust to external exhaust system (not shown) is from an 8” exhaust transition flange visible at top left. A viewscreen top hinge allows full opening for loading of instrumentation or equipment. The viewscreen is locked to prevent unauthorized opening.

Designed for Aseptic Compounding of Hazardous Chemotherapy and other Agents and IV Admixtures that can be Harmful to Pharmacy Personnel.

The Baker ChemoSHIELD^® Barrier Isolator offers a contained, leak-tight negative pressure work area suitable for hazardous pharmaceutical compounds, chemotherapy agents or IV admixtures that can be harmful to pharmacy personnel. ChemoSHIELD^® creates a unidirectional HEPA-filtered airflow of better than ISO Class 5 (Class 100) air cleanliness conditions within the negative pressure chamber to prevent migration of hazardous contaminants to the outside and to minimize cross-contamination across the direct compounding area.

Ergonomic Design Combines Convenience and Safety
With the introduction of the ChemoSHIELD^® negative pressure barrier isolator, The Baker Company offers an adaptive ergonomic design, combined with a unique airflow management system and proven containment technology, to improve comfort and increase productivity while assuring safety for both patient and pharmacy personnel alike.

• The adjustable stand permits work surface heights to be fixed at 36” (seated) or 45” (standing).
• The slanted viewscreen is made of shatterproof acrylic plastic, and angled at 10° for optimum ergonomic comfort and safety.
• The viewscreen remains closed and locked during normal operation.
• A spacious, negative pressure interchange (pass-thru chamber) allows safe and easy transfer of materials into or out of the chamber.
• The viewscreen top hinge allows full opening for initial loading of pharmacy instrumentation or equipment.
• Oval gloveports offer maximum reach to all interior surfaces for users of different heights, standing or sitting.
• Ambidextrous gloves are positioned in the main chamber to allow total access to the interior. CS600 has three gloves in main chamber. CS500 has two gloves in main chamber.
• The interchange door to the room includes one ambidextrous glove to permit manipulation of contents for surface decontamination of items moved into or out of the main chamber.

Cabinet Containment, Personnel and Product Protection
The barrier isolator pass-thru interchange and main chamber pressure (vs. ambient) are negative to the room. In the standard configuration the pass-thru interchange is slightly more negative than the main chamber to prioritize cleanliness in the main chamber while ensuring containment of hazardous compounds within the main work area.

The interchange door and interchamber door are mechanically interlocked to prevent both doors from being opened simultaneously.

• Individual supply and exhaust HEPA filters service the main chamber and interchange.
• Front-loading HEPA filters are 99.99% efficient. They provide better than ISO Class 5 (Class 100) air in both the main chamber and pass-thru interchange.
• Unidirectional (downflow) air removes airborne particulates from the work area and sweeps them to the exhaust HEPA filter.
• Exhaust filters are safely and easily removed via bag-out provision to contain hazardous compounds prior to disposal.
• A stainless steel air diffuser in the main chamber and interchange offers additional protection to supply filter.
• Key lock on cabinet front prevents unauthorized opening of fully-hinged front viewscreen that may compromise containment capability or aseptic environment.
• Mass airflow monitor audio/visual alarm system warns the user when the exhaust system has inadequate airflow.

The isolator main chamber pressure (vs. ambient) is negative to the room. Both the main chamber and interchange are always negative to the room, and provide protection to both product and personnel.

For aseptic compounding of hazardous chemotherapy agents and IV admixtures that can be harmful to pharmacy personnel	Pass-Thru Interchange Pressure	Work Chamber Pressure	Protection Profile Not intended for use with biologically hazardous materials			Exhaust
	Negative To Room	Negative To Room	Product Protection	Operator Protection	Environmental Protection
Standard Ratio Product/Personnel			Yes	Yes	Protects environment from particulates. Also protects environment from vapors and gases if connected to a treated exhaust system.	HEPA filter to facility exhaust system through hard connection via 8" collar.

Exclusive 10° slanted viewscreen reduces glare, improves comfort when working in the barrier isolator in a sitting (shown) or standing position.

Interchange
The HEPA-filtered interchange permits secure pass-thru in and out of the work area.

• The clear-view outer interchange door is left-hand swing. The door seals against peripheral gaskets to maintain internal negative pressure. This door is opened only when interchamber door is closed.
• The interchamber pass-thru door to the main work area swings open for easy transfer of materials between the interchange and main chamber while under negative pressure. This door is opened only when outer door is closed.
• Mechanical interlocks prevent both the interchamber door and exterior pass-thru door from being opened at the same time.

Airflow Plenum
ChemoSHIELD^® employs a high performance airflow system that provides optimum protection from particulates, together with extended filter life and reduced cost of ownership.

• The filter configuration creates an internal top to bottom airflow with a uniform piston effect to sweep particulates from the work area to the HEPA filter.
• The filter cross-section covers 100% of the work area.
• The unique plenum apportions and distributes air across, then through the HEPA supply filter, improving downflow uniformity and extending useful filter life.
• The filter mount provides a direct seal of the filter to the plenum and simplifies filter replacement.

Optimizes Interior Space, Simplifies Cleaning
The main chamber work area offers more than 5.1 sq. ft. of work space measuring 31”W x 24”D for the CS500. The CS600 offers more than 7.6 sq. ft. of work space measuring 46"W x 24"D. The interior back wall is vertical for maximum use of interior space.

• All interior surfaces of the main chamber and pass-thru interchange are Type 316 stainless steel for superior corrosion resistance.
• Back and side walls are polished to a non-glare, easy-to-clean finish.
• Interior surfaces can be accessed via gloves for sanitization.
• The interior cabinet ^7/16” radius corners permit easy wipe down.
• The sectional work surface trays are fully removable. Trays stack easily to either side to simplify changing of exhaust HEPA filters.
• Exterior, scratch-resistant, PermaWhite™ baked enamel finish provides resistance to demanding pharmacy environments.

Options and Accessories
Many options, accessories and modifications are factory installed and must be specified when ordering. Commonly requested options are listed below. For detailed information on accessories and modifications, contact The Baker Company.

• Vinyl bags for filter disposal
• Ergonomically adjustable footrest; field installed
• Seismic restraints; field installed
• Replacement gloves

To Order
For ordering information, terms and conditions of sale, contact The Baker Company or click here for the name of your authorized Baker Company representative.

ChemoSHIELD^® Design Features

1. Slanted viewscreen sloped 10° for the most comfortable head and elbow position when working; minimizes arm extension required to reach the work surface.

2. 8” exhaust collar for hard transition to facility exhaust system.

3. Fluorescent lamp on/off switch.

3a. Auxiliary switch for duplex electrical outlet(s).

4. Telescoping stand can be configured from 36” to 45” work surface height before glovebox is hard-connected to facility exhaust system.

5. Large, easy-to-read magnehelic gauges display negative pressure in interchange and work area with respect to room.

6. Fluorescent lighting minimizes heat output and improves eye comfort.

7. Hinged viewscreen is closed and locked for normal operation, opens fully for loading equipment or instrumentation.

8. Negative pressure interchange permits secure pass-thru in and out of the work area.

9. Negative pressure work area.

10. Interlocking interchamber pass-thru door restricts opening of inner-chamber outer door when interchamber door is open.

11. Oval gloveports permit maximum reach to all interior surfaces.

12. Front access to supply HEPA filters(1 each, main chamber and interchange) permits easier filter replacement.

13. Individual exhaust HEPA filters with bag-out design service the main chamber and interchange.

14. Audio/visual mass airflow monitor warns of inadequate airflow.

Controls
Because the cabinet airflow is created by a facility exhaust system external to the cabinet, the need for on-board controls is minimal.

• Large format, easy-to-read independent magnehelic gauges are positioned side-by-side to indicate relative negative pressure in the pass-thru interchange and the main work area with respect to the room.
• The externally mounted fluorescent lamps are controlled by an on/off switch on the main control panel.
• Mass airflow monitor measures airflow in exhaust and warns users of inadequate exhaust airflow (audible/visual).

Functional Utilities

• A single power cord for electrical connection is included.
• Externally mounted fluorescent lamps illuminate both the pass-thru interchange and work area while minimizing heat buildup in the cabinet.
• An ergonomically styled multi-position IV bar allows hanging of IV bags or bottles.
• Duplex outlet, ground-fault interrupt (GFI), 115V, AC, with weather-proof cover

Purchase Specification
ChemoSHIELD^® Barrier Isolator (negative pressure)
1. Cabinet shall maintain a negative pressure in both the work area and the interchange.
2. Cabinet shall provide better than ISO Class 5 (Class 100) HEPA-filtered air across 100% of the work surface and in the interchange.
3. Filtered unidirectional airflow provides better than ISO Class 5 (Class 100) air cleanliness conditions within the chamber. Gas-tight construction coupled with negative pressure prevents contaminants from the outside from entering the chamber and contaminants from the work area from migrating to the outside.
4. Work surface airflow shall be from top-to-bottom to achieve a piston effect, sweeping particulates from the work area to the HEPA filter.
5. Cabinet interchange negative pressure shall be visually verifiable by an independent magnehelic gauge on the main control panel.
6. The cabinet interchange outer door shall be of clear-view, shatter-proof polycarbonate with left-hand swing.
7. The cabinet interchamber door to the work area shall be 12 Ga., 316 SS with hinge for opening.
8. Cabinet work area negative pressure shall be visually verifiable by an independent magnehelic gauge on the main control panel.
9. The hinged viewscreen shall be slanted at an angle of 10° from vertical.
10. The viewscreen shall be capable of fully opening to load equipment or instruments.
11. The hinged viewscreen shall have a key lock to prevent unauthorized opening.
12. Viewscreen shall be constructed of shatterproof clear polycarbonate.
13. Viewscreen shall have three gloveports for the CS600. Two gloveports for the CS500. Gloves shall be nitrile rubber. Gloves are ambidextrous.
14. Stainless steel gloveports shall be oval to permit easy reach to all work surface areas.
15. The pass-thru interchange shall have one oval gloveport with a nitrile ambidextrous rubber glove.
16. All contaminated ducts, plenums and work area side walls shall be permanent metal construction and maintained under negative pressure.
17. Dimensions of the cabinet interior shall be apportioned as follows:
       a. Work area:
         CS500 - 31"W x 24"F x 25"H
         CS600 - 46”W x 24”F-B x 25”H
       b. Interchange:
         CS500/600 - 17½”W x 24”F-B x 25”H
18. Cabinet shall employ plenum to provide more uniform airflow to the supply filter.
19. Supply HEPA filters shall be front-loading.
20. Exhaust HEPA filters shall be bag-out design.
21. Plenum assembly shall be provided to allow the filters to be directly clamped to the plenum against a closed-cell neoprene gasket. The plenum applies force to full perimeter of filters, rather than point force.
22. Complete unit shall be certified by Underwriters Laboratory (UL) for electrical, fire and personal safety.
23. Cabinet exterior construction:
      a. Seal panels of 16-gauge, cold-rolled steel
      b. Dress panels of 18-gauge, cold-rolled steel, painted PermaWhite™.
24. Cabinet interior (work area) construction shall be one-piece, 16-gauge, Type 316 stainless steel, with a smooth, ^7/16” radius between rear and side walls, and easily cleanable, radiused corners on the work surface tray.
25. Work area side walls and rear wall to be one-piece construction.
26. A straight back wall shall be provided to maximize work area and easily accommodate pharmacy equipment.
27. Work area shall be outfitted with protected work area duplex outlet with weatherproof cover and circuit breaker.
28. Cabinet shall have a unitized drain pan with ^7/16” radius on all sides and a fully-removable work surface to facilitate cleaning.
29. A Type 316 stainless steel air diffuser and filter protector shall be provided in work area and pass-thru chamber (Interchange).
30. Each unit, before shipping, shall have a complete physical test to assure cabinet meets performance requirements. A copy of this test will be provided with the unit.
31. External adjustable damper provided to compensate for changing resistance of exhaust and supply filters.
32. A single power cord and plug shall be provided for electrical power source.
33. The unit shall have standard HEPA filters for a protection effectiveness of 99.99% when filtering particles of 0.3 micron size.
34. The unit shall be configurable for use while sitting or standing.
35. The unit shall include an adjustable stand with telescoping legs to allow the work surface height to be fixed at 36” or 45”.
36. Cabinet shall pass a 30 minute leak test per the American Glove Box Society standard.

Warranty
The Baker Company, Inc., expressly represents and warrants all goods (a) to be as specified (and described) in The Baker Company catalogs and literature, and (b) to be free under normal use, service and testing (all as described in The Baker Company catalogs and literature) from defects in material and workmanship for a period of thirty-six months from the invoice date.

The exclusive remedy for any breach or violation of this warranty is as follows: The Baker Company, Inc., will F.O.B Sanford, Maine, furnish without charge repairs to or replacement of the parts or equipment which proved defective in material or workmanship. No claim may be made for any incidental or consequential damages.

THIS WARRANTY IS EXPRESSLY IN LIEU OF ALL OTHER WARRANTIES, EXPRESSED OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE UNLESS OTHERWISE AGREED IN WRITING SIGNED BY THE BAKER COMPANY. (THE BAKER COMPANY SHALL NOT BE RESPONSIBLE FOR ANY IMPROPER USE, INSTALLATION, SERVICE OR TESTING OF THE GOODS.)